
Brain tumors are the most common pediatric solid neoplasm and the major cause of cancer-related morbidity of childhood and death. While most of the adult brain tumor appears in the brain supratentorial and large, the majority of brain tumors in children are infratentorial and arising in the posterior fossa, especially the cerebellum. Results from a malignant tumor of the cerebellum can not be accepted despite aggressive treatment (surgery, radiation and / or chemotherapy) that are harmful to brain development. Novel treatments / oncolytic virotherapy approach is needed.
Preclinical and clinical studies have previously shown that genetically engineered herpes simplex virus oncolytic (HSV-1) G207 safely can target a malignancy cerebellar and has the potential to induce an immune response anti-tumor on local sites and away from the disease, including metastatic spine disease and leptomeningeal. Here, we outline the rationale, design and significance of the first clinical trial the first-in-humans Phase immunotherapy targeting malignancy cerebellar recurrent HSV G207 in combination with low doses of radiation alone (5 Gy), designed to increase the replication of the virus and the innate and adaptive immune responses.
We discuss the unique challenges of intratumoral inoculation with the virus via the catheter into the tumor of the cerebellum. trial using one arm, open-label, the traditional 3 + 3 design with four dose cohorts. The main objective is to assess the safety and tolerability of a G207 with radiation in recurrent / progressive cerebellar malignant tumor of children. After a biopsy to prove relapse / progress, 1-4 intratumoral catheter will be placed followed by controlled-level G207 infusion over 6 hours followed by the removal of the catheter at the bedside.
Radiation will be given within 24 hours of virus inoculation. Patients will be closely monitored for toxicity and viral shedding. Efficacy will be assessed by measuring the response of radiography, the performance scores, progression-free and overall survival, and quality of life. The data obtained will be invaluable in our efforts to produce therapies more effective and less toxic to children with high-grade brain tumors.

Cerebrospinal Fluid of amyloid beta, Level Tau, apolipoprotein, and one H-MRS Brain metabolites in Alzheimer’s Disease: A Systematic Review
Background: There is strong evidence that the neurochemical changes measured by proton magnetic resonance spectroscopy (1H-MRS) occur at different phases of Alzheimer’s disease (AD). However, the extent of neurochemical changes associated with AD biomarkers are validated and / or apolipoprotein (APOE) ε4 not yet been established.
Objectives: This systematic review analyzing the evidence provided in (1) changes in neurochemistry; and (2) the relationship between brain metabolites and validated cerebrospinal fluid biomarkers, and / or APOE in AD.
Methods: PubMed, Cochrane, Scopus, and gray literature were systematically screened for the study deemed suitable for the purpose of the current systematic review.
Results: Twenty-four articles met the inclusion criteria. Decreased levels of N-acetyl aspartate (NAA), NAA / (creatine) Cr and NAA / (myo-inositol) ml, and increased ml, ml / Cr, Cho (choline) / Cr, ml / NAA was found in the posterior cingulate cortex / precuneus. Ml increase was associated with increased levels of tau, reduced NAA / Cr is associated with increased tau. ml / Cr was negatively correlated with Aβ42, and ml / Cr was positively correlated with t-tau.
![]() PPQ-102 |
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HY-14179 | MedChemExpress | 100mg | EUR 1221 |
![]() BGB-102 |
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HY-15732 | MedChemExpress | 10mg | EUR 6041 |
![]() EL-102 |
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HY-16187 | MedChemExpress | 10mM/1mL | EUR 376 |
![]() MM-102 |
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B1582-2 | ApexBio | 2 mg | EUR 128 |
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase. |
![]() MM-102 |
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B1582-20 | ApexBio | 20 mg | EUR 593 |
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase. |
![]() MM-102 |
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B1582-5 | ApexBio | 5 mg | EUR 212 |
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase. |
![]() PPQ-102 |
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B3504-10 | ApexBio | 10 mg | EUR 242 |
![]() PPQ-102 |
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B3504-5 | ApexBio | 5 mg | EUR 151 |
![]() PPQ-102 |
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B3504-50 | ApexBio | 50 mg | EUR 863 |
![]() PM 102 |
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B5517-1 | ApexBio | 1 mg | EUR 601 |
![]() p38 antibody |
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70R-51505 | Fitzgerald | 100 ul | EUR 268 |
Description: Purified Polyclonal p38 antibody |
![]() p38 antibody |
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70R-51506 | Fitzgerald | 100 ul | EUR 287 |
Description: Purified Polyclonal p38 antibody |
![]() anti-p38 |
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YF-PA11120 | Abfrontier | 50 ug | EUR 363 |
Description: Mouse polyclonal to p38 |
![]() anti-p38 |
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YF-PA11121 | Abfrontier | 100 ug | EUR 403 |
Description: Rabbit polyclonal to p38 |
![]() anti-p38 |
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YF-PA23519 | Abfrontier | 50 ul | EUR 334 |
Description: Mouse polyclonal to p38 |
![]() anti-p38 |
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YF-PA23520 | Abfrontier | 50 ul | EUR 334 |
Description: Mouse polyclonal to p38 |
![]() anti-p38 |
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YF-PA23521 | Abfrontier | 50 ul | EUR 334 |
Description: Mouse polyclonal to p38 |
![]() p38 protein |
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E20-80078 | EnoGene | 20ug | EUR 408 |
![]() p38 protein |
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E20-80079 | EnoGene | 20ug | EUR 408 |
![]() p38 Antibody |
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20-abx133223 | Abbexa |
|
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![]() p38 Antibody |
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20-abx007541 | Abbexa |
|
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![]() p38 Antibody |
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abx236076-100ug | Abbexa | 100 ug | EUR 481 |
![]() p38 Antibody |
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20-abx141038 | Abbexa |
|
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![]() p38 Antibody |
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35478-100ul | SAB | 100ul | EUR 390 |
![]() p38 Antibody |
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48644-100ul | SAB | 100ul | EUR 333 |
![]() p38 Antibody |
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48644-50ul | SAB | 50ul | EUR 239 |
![]() 5(6)-FAM [5-(and-6)-Carboxyfluorescein] *CAS 72088-94-9* |
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102 | AAT Bioquest | 25 g | EUR 876 |
![]() BP-1-102 |
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HY-100493 | MedChemExpress | 100mg | EUR 1345 |
![]() MM-102 (TFA) |
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HY-12220A | MedChemExpress | 10mM/1mL | EUR 263 |
![]() SB-203580 p38 MAPK(p38 MAP kinase) Inhibitor |
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E1B1863 | EnoGene | 1mg | EUR 161 |
![]() p38 beta, Active |
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7763-100 | Biovision | EUR 4345 |
![]() p38 beta, Active |
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7763-5 | Biovision | EUR 370 |
![]() p38 MAPK antibody |
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70R-33398 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal p38 MAPK antibody |
![]() p38 MAPK antibody |
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70R-33400 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal p38 MAPK antibody |
![]() P38 MAPK antibody |
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70R-34325 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal P38 MAPK antibody |
![]() P38 MAPK antibody |
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70R-34327 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal P38 MAPK antibody |
![]() p38 MAPK Antibody |
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AF6455 | Affbiotech | 200ul | EUR 304 |
Description: p38 MAPK Antibody detects endogenous levels of total p38 MAPK. |
![]() p38 MAPK Antibody |
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AF6456 | Affbiotech | 200ul | EUR 304 |
Description: p38 MAPK Antibody detects endogenous levels of total p38 MAPK. |
![]() p38 MAPK Antibody |
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AF6457 | Affbiotech | 200ul | EUR 304 |
Description: p38 MAPK Antibody detects endogenous levels of total p38 MAPK. |
![]() p38 MAPK Antibody |
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ABF6456 | Lifescience Market | 100 ug | EUR 438 |
![]() Anti-p38 (3D5) |
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YF-MA12551 | Abfrontier | 200 ul | EUR 363 |
Description: Mouse monoclonal to p38 |
![]() Anti-p38 (1C9) |
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YF-MA12552 | Abfrontier | 100 ug | EUR 363 |
Description: Mouse monoclonal to p38 |
![]() anti-Crk p38 |
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YF-PA11088 | Abfrontier | 50 ul | EUR 363 |
Description: Mouse polyclonal to Crk p38 |
![]() anti-Crk p38 |
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YF-PA11089 | Abfrontier | 50 ug | EUR 363 |
Description: Mouse polyclonal to Crk p38 |
![]() anti-Crk p38 |
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YF-PA11090 | Abfrontier | 100 ug | EUR 403 |
Description: Rabbit polyclonal to Crk p38 |
![]() anti-AIMP2/p38 |
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YF-PA15507 | Abfrontier | 50 ug | EUR 363 |
Description: Mouse polyclonal to AIMP2/p38 |
![]() anti-Crk p38 |
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YF-PA23509 | Abfrontier | 50 ul | EUR 334 |
Description: Mouse polyclonal to Crk p38 |
![]() P38 delta protein |
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30R-2868 | Fitzgerald | 5 ug | EUR 503 |
Description: Purified recombinant Human P38 delta protein |
![]() p38 alpha protein |
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30R-2870 | Fitzgerald | 5 ug | EUR 503 |
Description: Purified recombinant Human p38 alpha protein |
![]() p38 beta protein |
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30R-2875 | Fitzgerald | 5 ug | EUR 503 |
Description: Purified recombinant Human p38 beta protein |
![]() p38 MAPK antibody |
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20R-1572 | Fitzgerald | 100 ug | EUR 705 |
Description: Rabbit polyclonal p38 MAPK antibody |
![]() P38 MAPK antibody |
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20R-2087 | Fitzgerald | 50 ug | EUR 281 |
Description: Rabbit polyclonal P38 MAPK antibody |
![]() P38 MAPK antibody |
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20R-2088 | Fitzgerald | 50 ug | EUR 281 |
Description: Rabbit polyclonal P38 MAPK antibody |
![]() P38 MAPK antibody |
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20R-2403 | Fitzgerald | 50 ug | EUR 281 |
Description: Rabbit polyclonal P38 MAPK antibody |
![]() p38 MAPK antibody |
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20R-2950 | Fitzgerald | 100 ul | EUR 393 |
Description: Rabbit polyclonal p38 MAPK antibody |
![]() p38 MAPK antibody |
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10R-8422 | Fitzgerald | 100 ul | EUR 393 |
Description: Mouse monoclonal p38 MAPK antibody |
![]() Anti-p38 alpha |
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DB-1039 | DB Biotech | 100 tests | EUR 474 |
![]() Anti-p38 beta |
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DB-1040 | DB Biotech | 100 tests | EUR 474 |
![]() Anti-p38 gamma |
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DB-1041 | DB Biotech | 100 tests | EUR 474 |
![]() Anti-p38 delta |
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DB-1042 | DB Biotech | 100 tests | EUR 474 |
![]() Anti-p38-a |
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DB-161-0.05 | DB Biotech | 50 μl | EUR 269 |
![]() Anti-p38-a |
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DB-161-0.1 | DB Biotech | 100 μl | EUR 422 |
![]() Anti-p38-b |
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DB-162-0.05 | DB Biotech | 50 μl | EUR 269 |
![]() Anti-p38-b |
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DB-162-0.1 | DB Biotech | 100 μl | EUR 422 |
![]() Anti-p38-g |
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DB-163-0.05 | DB Biotech | 50 μl | EUR 269 |
![]() Anti-p38-g |
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DB-163-0.1 | DB Biotech | 100 μl | EUR 422 |
![]() Anti-p38-d |
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DB-164-0.05 | DB Biotech | 50 μl | EUR 269 |
![]() Anti-p38-d |
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DB-164-0.1 | DB Biotech | 100 μl | EUR 422 |
![]() Anti-p38 alpha |
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DB1039 | DB Biotech | 100 tests | EUR 474 |
![]() Anti-p38 beta |
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DB1040 | DB Biotech | 100 tests | EUR 474 |
![]() Anti-p38 gamma |
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DB1041 | DB Biotech | 100 tests | EUR 474 |
![]() Anti-p38 delta |
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DB1042 | DB Biotech | 100 tests | EUR 474 |
![]() anti-p38 MAPK |
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LF-PA0160 | Abfrontier | 100 ul | EUR 334 |
Description: Rabbit polyclonal to p38 MAPK |
![]() Anti-p38 antibody |
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PAab06076 | Lifescience Market | 100 ug | EUR 355 |
![]() p38 Polyclonal Antibody |
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ES4837-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
![]() p38 Polyclonal Antibody |
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ES4837-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
![]() p38 Polyclonal Antibody |
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ES4838-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
![]() p38 Polyclonal Antibody |
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ES4838-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
![]() p38 Polyclonal Antibody |
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ES8347-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA |
![]() p38 Polyclonal Antibody |
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ES8347-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA |
![]() p38 Polyclonal Antibody |
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ES3111-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
![]() p38 Polyclonal Antibody |
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ES3112-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
![]() p38 Polyclonal Antibody |
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ES3111-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
![]() p38 Polyclonal Antibody |
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ES3112-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
![]() p38 (pY323) Antibody |
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20-abx133058 | Abbexa |
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![]() p38 (pY182) Antibody |
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20-abx134951 | Abbexa |
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![]() p38 Polyclonal Antibody |
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ABP53838-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
![]() p38 Polyclonal Antibody |
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ABP53838-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
![]() p38 Polyclonal Antibody |
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ABP53838-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
![]() p38 Polyclonal Antibody |
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ABP53839-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
![]() p38 Polyclonal Antibody |
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ABP53839-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
![]() p38 Polyclonal Antibody |
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ABP53839-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
![]() Anti-p38 Antibody |
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A00176 | BosterBio | 100ul | EUR 397 |
Description: Rabbit Polyclonal Antibody for p38 Antibody (MAPK14) detection.tested for WB in Human, Mouse, Rat. |
![]() p38 Polyclonal Antibody |
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ABP52112-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
![]() p38 Polyclonal Antibody |
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ABP52112-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
![]() p38 Polyclonal Antibody |
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ABP52112-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
![]() p38 Polyclonal Antibody |
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ABP52113-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
![]() p38 Polyclonal Antibody |
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ABP52113-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
![]() p38 Polyclonal Antibody |
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ABP52113-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
![]() p38 Blocking Peptide |
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20-abx061736 | Abbexa |
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![]() p38 Blocking Peptide |
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20-abx062080 | Abbexa |
|
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![]() p38 (pT180) Antibody |
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20-abx009863 | Abbexa |
|
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![]() p38 MAPK Antibody |
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20-abx012798 | Abbexa |
|
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![]() p38 MAPK Antibody |
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20-abx012875 | Abbexa |
|
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![]() p38 Polyclonal Antibody |
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ABP57354-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
![]() p38 Polyclonal Antibody |
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ABP57354-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
![]() p38 Polyclonal Antibody |
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ABP57354-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
![]() p38 MAPK Antibody |
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abx236077-100ug | Abbexa | 100 ug | EUR 481 |
![]() p38 Blocking Peptide |
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20-abx161932 | Abbexa |
|
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![]() Anti-p38 antibody |
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STJ94876 | St John's Laboratory | 200 µl | EUR 197 |
Description: Rabbit polyclonal to p38. |
![]() Anti-p38 antibody |
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STJ94877 | St John's Laboratory | 200 µl | EUR 197 |
Description: Rabbit polyclonal to p38. |
![]() Anti-p38 antibody |
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STJ94878 | St John's Laboratory | 200 µl | EUR 197 |
Description: p38 is a protein encoded by the MAPK14 gene which is approximately 41,2 kDa. p38 is localised to the cytoplasm and nucleus. It is involved in activated TLR4 signalling, the IL-2 pathway, toll-like receptor signalling pathways, the VEGF signalling pathway and 4-1BB pathway. This protein falls under the MAP kinase family. It acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. p38 is expressed in the brain, heart, placenta, pancreas and skeletal muscle. Mutations in the MAPK14 gene may result in patellar tendinitis and lumbosacral lipoma. STJ94878 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of p38 protein. |
![]() Anti-p38 antibody |
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STJ94879 | St John's Laboratory | 200 µl | EUR 197 |
Description: Rabbit polyclonal to p38. |
![]() Anti-P38 antibody |
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STJ98898 | St John's Laboratory | 200 µl | EUR 197 |
Description: Mouse monoclonal to P38. |
![]() Anti-P38 antibody |
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STJ98899 | St John's Laboratory | 200 µl | EUR 197 |
Description: Mouse monoclonal to P38. |
![]() Anti-p38 antibody |
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STJ97615 | St John's Laboratory | 200 µl | EUR 197 |
Description: Rabbit polyclonal to p38. |
![]() p38 Polyclonal Antibody |
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41305-100ul | SAB | 100ul | EUR 252 |
![]() p38 Polyclonal Antibody |
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41305-50ul | SAB | 50ul | EUR 187 |
![]() p38 Polyclonal Antibody |
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41306-100ul | SAB | 100ul | EUR 252 |
![]() p38 Polyclonal Antibody |
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41306-50ul | SAB | 50ul | EUR 187 |
![]() p38 alpha-MAPK14 |
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RA15053 | Neuromics | 100 ug | EUR 526 |
![]() p38 MAPK Antibody |
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49379-100ul | SAB | 100ul | EUR 333 |
![]() p38 MAPK Antibody |
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49379-50ul | SAB | 50ul | EUR 239 |
![]() anti- p38 antibody |
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FNab06076 | FN Test | 100µg | EUR 505.25 |
Description: Antibody raised against p38 |
![]() HG-10-102-01 |
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HY-13488 | MedChemExpress | 10mM/1mL | EUR 219 |
![]() Biotin-MBP(94 - 102) |
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5-00804 | CHI Scientific | 4 x 5mg | Ask for price |
![]() Polyclonal SAP 102 Antibody |
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APR13193G | Leading Biology | 0.05ml | EUR 659 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SAP 102 . This antibody is tested and proven to work in the following applications: |
![]() HG-10-102-01 |
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B1262-10 | ApexBio | 10 mg | EUR 303 |
Description: HG-10-102-01 is a potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2) with the IC50 values of 20.3nM and 3.2nM for wild type LRRK2 and LRRK2 [G1019S], respectively [1]. |
![]() HG-10-102-01 |
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B1262-25 | ApexBio | 25 mg | EUR 502 |
Description: HG-10-102-01 is a potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2) with the IC50 values of 20.3nM and 3.2nM for wild type LRRK2 and LRRK2 [G1019S], respectively [1]. |
![]() HG-10-102-01 |
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B1262-5 | ApexBio | 5 mg | EUR 193 |
Description: HG-10-102-01 is a potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2) with the IC50 values of 20.3nM and 3.2nM for wild type LRRK2 and LRRK2 [G1019S], respectively [1]. |
![]() HG-10-102-01 |
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B1262-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 192 |
Description: HG-10-102-01 is a potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2) with the IC50 values of 20.3nM and 3.2nM for wild type LRRK2 and LRRK2 [G1019S], respectively [1]. |
![]() HG-10-102-01 |
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B1262-50 | ApexBio | 50 mg | EUR 821 |
Description: HG-10-102-01 is a potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2) with the IC50 values of 20.3nM and 3.2nM for wild type LRRK2 and LRRK2 [G1019S], respectively [1]. |
![]() CART (55-102) (rat) |
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B5412-.1 | ApexBio | 100 ug | EUR 502 |
![]() CART (55-102) (human) |
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B5413-.1 | ApexBio | 100 ug | EUR 447 |
![]() CART (55-102) (human) |
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H-4444.0100 | Bachem | 0.1mg | EUR 393 |
Description: Sum Formula: C225H365N65O65S7; CAS# [214050-22-3] |
![]() CART (55-102) (human) |
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H-4444.0500 | Bachem | 0.5mg | EUR 1482 |
Description: Sum Formula: C225H365N65O65S7; CAS# [214050-22-3] |
![]() CART (55-102) (human) |
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H-4444.1000 | Bachem | 1.0mg | EUR 2207 |
Description: Sum Formula: C225H365N65O65S7; CAS# [214050-22-3] |
![]() CART (55-102) (rat) |
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H-4446.0100 | Bachem | 0.1mg | EUR 393 |
Description: Sum Formula: C226H367N65O65S7; CAS# [209615-79-2] |
![]() CART (55-102) (rat) |
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H-4446.0500 | Bachem | 0.5mg | EUR 1482 |
Description: Sum Formula: C226H367N65O65S7; CAS# [209615-79-2] |
![]() CART (55-102) (rat) |
|||
H-4446.1000 | Bachem | 1.0mg | EUR 2207 |
Description: Sum Formula: C226H367N65O65S7; CAS# [209615-79-2] |
![]() Mouse P38 Mitogen-activated Protein Kinase (MAPK P38) CLIA Kit |
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abx197397-96tests | Abbexa | 96 tests | EUR 825 |
![]() Mouse MAPK P38(P38 Mitogen-activated Protein Kinase) ELISA Kit |
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EM1199 | FN Test | 96T | EUR 524.1 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.75 ng/ml |
![]() p38 MAPK antibody (Thr180) |
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70R-37313 | Fitzgerald | 100 ug | EUR 349 |
Description: Rabbit Polyclonal p38 MAPK antibody (Thr180) |
![]() p38 MAPK antibody (Tyr182) |
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70R-37314 | Fitzgerald | 100 ug | EUR 349 |
Description: Rabbit Polyclonal p38 MAPK antibody (Tyr182) |
![]() p38 MAPK antibody (Tyr322) |
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70R-33397 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal p38 MAPK antibody (Tyr322) |
![]() P38 MAPK antibody (Thr179) |
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70R-34324 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal P38 MAPK antibody (Thr179) |
![]() P38 MAPK antibody (Tyr182) |
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70R-34326 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal P38 MAPK antibody (Tyr182) |
![]() p38 MAPK Blocking Peptide |
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AF6455-BP | Affbiotech | 1mg | EUR 195 |
![]() p38 MAPK Blocking Peptide |
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AF6456-BP | Affbiotech | 1mg | EUR 195 |
![]() p38 MAPK Blocking Peptide |
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AF6457-BP | Affbiotech | 1mg | EUR 195 |
![]() Phospho p38 (Tyr323) Antibody |
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A1984-100 | Biovision | 100 µl | EUR 379 |
![]() p38 MAP Kinase antibody |
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20R-1458 | Fitzgerald | 100 ug | EUR 673 |
Description: Rabbit polyclonal p38 MAP Kinase antibody |
![]() p38 MAP Kinase Antibody |
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3114-100 | Biovision | EUR 343 |
![]() p38 MAP Kinase Antibody |
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3114-30T | Biovision | EUR 146 |
![]() p38 MAP Kinase antibody |
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70R-11620 | Fitzgerald | 100 ug | EUR 418 |
Description: Rabbit polyclonal p38 MAP Kinase antibody |
![]() Phospho-p38 MAPK antibody |
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70R-11824 | Fitzgerald | 100 ug | EUR 525 |
Description: Rabbit polyclonal Phospho-p38 MAPK antibody |
![]() Phospho-p38 MAPK Antibody |
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3438-100 | Biovision | EUR 425 |
![]() p38 gamma/delta Antibody |
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DF10341 | Affbiotech | 200ul | EUR 304 |
Description: p38-delta/gamma Antibody detects endogenous levels of p38-delta/gamma. |
![]() anti-p38 MAPK (6A1) |
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LF-MA0126 | Abfrontier | 100 ul | EUR 334 |
Description: Mouse monoclonal to p38 MAPK |
![]() anti-p38 MAPK (3D5) |
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LF-MA10188 | Abfrontier | 50 ug | EUR 363 |
Description: Mouse monoclonal to p38 MAPK |
![]() p38 MAPK-IN-2 |
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HY-U00324 | MedChemExpress | 10mg | EUR 3700 |
![]() p38 MAPK Polyclonal Antibody |
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ES8901-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against p38 MAPK from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
![]() p38 MAPK Polyclonal Antibody |
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ES8901-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against p38 MAPK from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
![]() P38 (1G1) Monoclonal Antibody |
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EM1369-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Mouse Monoclonal antibody against P38 (1G1) from Human/ Mouse/ Rat. This antibody is tested and validated for IHC |
![]() P38 (1G1) Monoclonal Antibody |
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EM1369-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Mouse Monoclonal antibody against P38 (1G1) from Human/ Mouse/ Rat. This antibody is tested and validated for IHC |
![]() p38 MAPK-IN-1 |
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HY-12839 | MedChemExpress | 5mg | EUR 533 |
![]() Anti-AIMP2/p38 Antibody |
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PA1481 | BosterBio | 100ug/vial | EUR 334 |
![]() Anti-Crk p38 Antibody |
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PB9101 | BosterBio | 100ug/vial | EUR 334 |
![]() p38 (pT180 / Y182) Antibody |
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20-abx133560 | Abbexa |
|
|
![]() p38 MAPK Rabbit pAb |
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A10832-100ul | Abclonal | 100 ul | EUR 384 |
![]() p38 MAPK Rabbit pAb |
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A10832-200ul | Abclonal | 200 ul | EUR 554 |
![]() p38 MAPK Rabbit pAb |
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A10832-20ul | Abclonal | 20 ul | EUR 183 |
![]() p38 MAPK Rabbit pAb |
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A10832-50ul | Abclonal | 50 ul | EUR 265 |
![]() p38 MAPK Rabbit pAb |
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A11340-100ul | Abclonal | 100 ul | EUR 308 |
![]() p38 MAPK Rabbit pAb |
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A11340-200ul | Abclonal | 200 ul | EUR 459 |
![]() p38 MAPK Rabbit pAb |
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A11340-20ul | Abclonal | 20 ul | EUR 183 |
![]() p38 MAPK Rabbit pAb |
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A11340-50ul | Abclonal | 50 ul | EUR 223 |
![]() p38 (pY182) Blocking Peptide |
|||
20-abx061650 | Abbexa |
|
|
![]() p38 (pT180) Blocking Peptide |
|||
20-abx062081 | Abbexa |
|
|
![]() p38 MAPK (pT180) Antibody |
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abx011783-100ug | Abbexa | 100 ug | EUR 439 |
![]() p38 MAPK (pY182) Antibody |
|||
20-abx011784 | Abbexa |
|
|
![]() p38 MAPK (pY322) Antibody |
|||
20-abx011785 | Abbexa |
|
|
![]() p38 MAPK Rabbit pAb |
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A5521-100ul | Abclonal | 100 ul | EUR 308 |
![]() p38 MAPK Rabbit pAb |
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A5521-200ul | Abclonal | 200 ul | EUR 459 |
![]() p38 MAPK Rabbit pAb |
|||
A5521-20ul | Abclonal | 20 ul | EUR 183 |
![]() p38 MAPK Rabbit pAb |
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A5521-50ul | Abclonal | 50 ul | EUR 223 |
![]() p38 MAPK Rabbit pAb |
|||
A14401-100ul | Abclonal | 100 ul | EUR 308 |
![]() p38 MAPK Rabbit pAb |
|||
A14401-200ul | Abclonal | 200 ul | EUR 459 |
![]() p38 MAPK Rabbit pAb |
|||
A14401-20ul | Abclonal | 20 ul | EUR 183 |
![]() p38 MAPK Rabbit pAb |
|||
A14401-50ul | Abclonal | 50 ul | EUR 223 |
![]() p38 MAPK Polyclonal Antibody |
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ABP59793-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of p38 MAPK from Human, Mouse, Rat. This p38 MAPK antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human p38 MAPK protein |
![]() p38 MAPK Polyclonal Antibody |
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ABP59793-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of p38 MAPK from Human, Mouse, Rat. This p38 MAPK antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human p38 MAPK protein |
![]() p38 MAPK Polyclonal Antibody |
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ABP59793-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of p38 MAPK from Human, Mouse, Rat. This p38 MAPK antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human p38 MAPK protein |
![]() p38 (pY323) Blocking Peptide |
|||
20-abx161669 | Abbexa |
|
|
NAA and reduced glutathione levels in APOE ε4 carriers. APOE ε4 modulatory exerts no effect on the NAA / Cr. There is an interaction between APOE ε4, Aβ42, and ml / Cr.
Conclusion: NAA, ml, NAA / Cr, NAA / ml and ml / Cr may be potentially useful biomarkers that might highlight the functional changes in the clinical stage of AD.